Sudden cardiac arrest (SCA) is a sudden and unexpected loss of pulse due to a collapse of the heart's electrical system, and is fatal without immediate medical care. Even with advances in resuscitation, SCA results in death in more than 9 out of 10 cases. Sudden cardiac death (SCD) is responsible for half of cardiovascular deaths in the US, with a total of 300,000 to 350,000 deaths each year.
While physicians currently identify patients at high risk for SCA by measuring the function of the heart's left ventricle, this method needs significant improvement. Conversely, most patients who suffer SCA are not currently classified as high-risk. There is a critical need to establish methods to identify patients in the general population who can benefit most from prevention efforts.
Welcome to PRESTONetwork.org! This website serves as the central hub for information, news, resources and education for the participating research study sites in the PREdiction of Sudden death in mulTi-ethnic cOmmunities (PRESTO) Network.
The PRESTO research study is conducted by the Arrhythmia Research Laboratory at the Cedars-Sinai Heart Institute, Cedars-Sinai Health System, Los Angeles. Dr. Sumeet S. Chugh (currently at the Cedars-Sinai Heart Institute) founded the Oregon Sudden Unexpected Death Study (Oregon SUDS) in 2002 to investigate predictors, mechanisms, and prevention strategies for SCA with the ultimate goal of significantly reducing the burden of sudden cardiac death. The Oregon SUDS is an observational, community-based study of SCA designed to identify predictors of SCA, with the goal of improving prevention. As of 2015 this study has been expanded to Ventura County, CA (PRESTO Ventura), creating the PRESTO Network. In addition, successful pilot projects have been completed in Oahu, HI and St Paul, MN, with the goal of these communities also joining the PRESTO Network in the future.
Currently, little data is available regarding incidence and predictors of SCA in non-white individuals. Compared to the relatively homogenous Oregon SUDS population (85% of the Portland, Oregon population is of white, European descent), the launch of PRESTO in the new study sites would enable us to enroll and study subjects from a large population of racially and ethnically diverse individuals. The PRESTO network aims to capture a wide range of racial and ethnic backgrounds to improve prediction and prevention of SCA.